Product photo · 10mg
Reports describe submitted samples for this amount and form.
PT-141
A drug studied for low sexual desire in a defined clinical population.
What does the amount mean?
10 mg is an amount of material. Read the label to see whether it means per vial, per tablet, or per package.
Read more1 vial · 10mg in each vial
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Lab resultsPT-141, explained
A drug studied for low sexual desire in a defined clinical population.
What it’s used for
Sexual desire in women
The approved bremelanotide medicine is for acquired low desire in premenopausal women. Trials found modest improvements in desire and distress.
Erections
Men report erectile-function use 45–60 minutes before sex. It is not approved for men.
Arousal and satisfaction
Reported uses include arousal, sexual satisfaction and performance anxiety.
What to expect
- 45–90 min
Effects start
- 2–4 hours
Peak effect
- 6–12 hours
Effects fade
Side effects & safety
Side effects
- Nausea — it affected 40% of people treated in the approved-product trials
- Flushing and headache
- Darkened skin patches (hyperpigmentation), which can be lasting
- A temporary rise in blood pressure and drop in heart rate
- Nasal irritation or bleeding with nasal use
- Slower stomach emptying, which can change how oral medicines are absorbed
Stop and get help if
- Chest pain
- Severe vomiting
- Changes in vision or headache
- Signs of an allergic reaction
- An erection lasting more than four hours
Avoid or check first
- Uncontrolled high blood pressure or known heart disease — the label lists both as contraindications
- Pregnant or could become pregnant — the label advises effective contraception and stopping if pregnancy is suspected
- Taking oral naltrexone for alcohol or opioid addiction — PT-141 lowers naltrexone levels
- Taking nitrates
In sport
- The reference reports: not on WADA’s banned list.
How much people usually take
Low sexual desire in women (FDA-approved)
As needed, max 1 dose/24 hr · abdomen/thigh · injectable
Male erectile dysfunction
As needed, 45–60 min before activity · injectable
Female arousal disorder
As needed, max 1 dose/24 hr · injectable
Low starting dose
Test dose to assess tolerance · injectable
HSDD symptom treatment
As needed, at least 45 minutes before sexual activity · SubQ autoinjector · Stop after 8 weeks without improvement · injectable
Erectile dysfunction (standard)
As needed, 30–45 min before; max 1 dose per 24 hours · nasal
Female sexual dysfunction
As needed, max 1 dose/24 hr · nasal
Upper dose
Only if lower doses don't work; max 1 dose per 24 hours · nasal
How to mix and store it
How many units do I draw?
How to mix5 steps
Wipe both tops
Wash your hands, then swab both rubber vial tops with alcohol. Let them dry.
Draw the water
Use a new sterile syringe to draw the water volume selected in the calculator.
Run it down the wall
Introduce the water slowly down the inside glass wall, rather than directly onto the powder.
Swirl, don’t shake
Gently swirl or roll the vial. Allow time for the powder to dissolve.
Label the vial
Write the preparation date and the amount and final volume on the vial label.
Injecting under the skinWhere, rotating sites, which syringe
Where
Subcutaneous injections go into the fatty layer beneath the skin. Common sites include the abdomen, outer thigh and upper arm. Keep at least 5 cm from the navel and avoid bruised, irritated or damaged skin.
Rotate sites
Change the spot each time. Clean the skin and let it dry.
Single-use equipment
Use a new sterile needle and syringe each time. Place used needles in a sharps container.
Storage
Storage
Refrigerated at 2-8°C. Reported period: 30 days.
Combining it with others
Don’t combine
- Melanotan II
They affect the same hormone system.
Use caution
- Semaglutide
Nausea can add up.
- Tirzepatide
Nausea can add up.
- Retatrutide
Nausea can add up.
- Survodutide
Nausea can add up.
- Mazdutide
Nausea can add up.
- Orforglipron
Nausea can add up.
- Melanotan I
Both can cause nausea and flushing.
- Tesofensine
Higher blood pressure.
Other combinations
More about these combinations
- Oxytocin
They work through different signals.
What the research says
The question being studied
Two 24-week RECONNECT trials assigned 1,267 women who had not reached menopause and had a diagnosed low-desire disorder to study groups. The main analysis included 1,202 people and measured desire and related distress.
How long it stays in your body
Half-life is the time it takes for the amount in the body to fall by half. It does not tell you how long effects last.
Drag to see how much is left over time.
What it’s made of
Sequence 7 · N → C
- Nle
- Asp
- His
- D-Phe
- Arg
- Trp
- Lys
N-acetylated cyclic heptapeptide. The label writes Ac-Nle-cyclo-(Asp-His-D-Phe-Arg-Trp-Lys-OH); the simple residue tokens do not encode ring connectivity.
Molecular notes
Bremelanotide acetate / PT-141 reference molecule. The acetate formula and free-base mass use different stated reference conventions; neither verifies the Monroe vial.
Lab results
10mg · 2 linked reports
- Purity · sample result
- 99.503% / 99.463% / 99.475%
- Amount found · PT-141
- Sample 1: 11.2 mgSample 2: 11.62 mgSample 3: 11.07 mg
Separate sample results, in report order.
Purity & amount
Sample batch PT04
Bacterial toxin test
Sample batch PT04
These are submitted-sample results, separate from general research or popularity ratings. Report presentation: Peptify Analytics. Source laboratory: Janoshik Analytical. The connection to the batch you would receive is not confirmed here.
Videos worth watching
Research conversations, with their original context.
Video resources are not available for this guide.
Read the original sourcesProduct details
- Form
- Vial
- Amount
- 10mg
Sources & further reading
Follow each reference to its original publication or documentation.
- Official documentation · 2024Vyleesi prescribing information, March 2024 (opens in a new tab)
- Primary research · 2019Bremelanotide RECONNECT phase 3 trials (opens in a new tab)
- Reference reportPepSavvy: PT-141 (opens in a new tab)
- Official documentationCDC: Preventing Unsafe Injection Practices (opens in a new tab)
- Official documentationMedlinePlus: Subcutaneous injections (opens in a new tab)
Questions
What does 10mg mean?
It describes an amount of material in the unit stated on the label. It does not describe liquid volume, a dose, or how to prepare the product.
Read more about amountsDoes purity mean it is sterile?
No. Purity and sterility require different tests. An endotoxin result also does not establish sterility.
About testingCan I calculate concentration?
You need a mass in mg and either a final volume or a target concentration. IU and blends require separate, verified information.
Use the mixing helper for this amount ↑How can I get help with an order?
Open your order details to check its current status. Shipping and support information are available below.
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