Bromantane (Ladasten)
What it’s used for
Bromantane (Ladasten) is an adamantane-based small molecule, not a peptide, sold as a nootropic. People use it for fatigue, motivation, calm without sedation and endurance under stress. The main human evidence is an older 28-day study of 728 patients with fatigue disorders that had no comparison group.
- Less fatigue Small human studies Used for fatigue and low energy. In a 728-patient study of fatigue disorders, symptoms improved over 28 days.
- Motivation & drive Community reports Used for motivation and performance under stress.
- Calm without sedation Community reports Used to ease anxiety without drowsiness and for steadier mood and stress resilience.
- Endurance & recovery Community reports Used for endurance in heat or exhaustion, recovery and immune support.
What to expect
- Days 1–3
A stimulating effect within 1.5–2 hours of a dose
- Week 1
More energy
- Weeks 2–3
Full motivation effect
- Weeks 3–4
Peak performance reported
- After stopping
Effects reported to last 2–4 weeks
Side effects & safety
Side effects
- Side effects occurred in 3% of people in the 28-day patient study, and 0.8% stopped treatment
Stop and get help if
- Persistent agitation or trouble sleeping
- Racing thoughts or repetitive behavior
- New anxiety or mood changes
- Palpitations or chest discomfort
- Stomach upset or signs of an allergic reaction
Which symptoms mean call 911 or see a doctor
Avoid or check first if
- Taking MAOIs — theoretical risk of monoamine build-up
- Taking stimulants like Adderall or Ritalin — risk of dopamine overstimulation
- Drug-tested athletes — it's reported as WADA-prohibited
In sport
Banned in competition. Named as “bromantan” among the stimulants, so it’s banned in competition only.
Which peptides are banned in sport
How much people take
For every goal: Oral
- Fatigue (standard dose) Once daily in the morning 50 mg
- Full therapeutic dose Once daily or split 50 mg twice daily 100 mg
- Conservative start Once daily to assess tolerance 25 mg
- Physical performance enhancement Once daily, 1–2 hours before activity 50–100 mg
- Cognitive & mood support cycle Once daily for 2–4 weeks, then 1–2 weeks off 50 mg
Similar doses appear in 6 other sources
How to store it
How many units do I draw?
Room temp Keep away from moisture and light
Ready to use
The oral form doesn’t need mixing.
Is it OK to use?
Good signs
- White to off-white crystalline powder
Don’t use if
- Yellowing or clumping
Combining it with others
AI assessment Based on how each compound works, not on studies of the combination. How we assess
Use caution 5
- Semax Both lean stimulating. Together they can disturb sleep.
- NA Semax Amidate Both lean stimulating. Together they can disturb sleep.
- Adamax Both lean stimulating. Together they can disturb sleep.
- DSIP Opposite effects: DSIP is for sleep, this is stimulating.
- Tesofensine Both raise dopamine. Expect more jitters, poor sleep and a faster heart rate.
Can be combined 7
What the research says
Few human studies
- The main patient study had no comparison group, so placebo effects and natural recovery can't be ruled out.
- Results in patients with fatigue disorders don't show it sharpens thinking in healthy people.
- The clinical reports are older Russian studies; no recent controlled trial or human half-life result turned up in this review.
- Long-term safety is unknown; claims of no tolerance or dependence don't settle it.
What studies found
- Older uncontrolled patient study A 2010 study analyzed 728 patients with asthenic disorders treated for 28 days. Symptoms improved, but no randomized comparator is described in the abstract.
- Small molecule, not a peptide Bromantane is an adamantane-derived chemical. Its presence in peptide catalogs does not make peptide reconstitution or peptide half-life assumptions applicable.
- Recent evidence concerns product surveillance The 2025 laboratory survey investigated unregulated nootropics, including bromantane. It does not establish a treatment effect or a dosing regimen.
A half-life hasn’t been verified for this compound.
What it’s made of
- Length
- Small molecule (adamantane derivative)
- Molecular weight
- 306.24 Da
- Formula
- C 16 H 20 BrN
An exact sequence has not been verified for this form.
Chemical free compound; not an injectable peptide formulation.
Length and weight come from a reference listing and were not independently confirmed.
Sources
Sources 14
How this page was made
How it may work: Dopamine-synthesis enzyme and GABA-related mechanisms are described; genomic explanations do not prove clinical benefit.
Preparation in studies: No product-specific preparation or stability instruction was verified.
Research last checked: Oct 12, 2026 (a targeted search, not a full review).
Community doses, how long people take it, timing and storage are compiled with AI from public peptide guides, clinics and forums, cross-checked against other sources where we could, and rewritten in plain language. “Combining it with others” is an AI assessment of how the compounds work. Study notes are written from each paper’s abstract where one exists. How we source
Original source guide